Malaria-LAMP Kit

First molecular diagnostic test launched for the detection of malaria caused by Plasmodium vivax parasites.

Malaria-LAMP is a comprehensive molecular solution introduced for the diagnosis of malaria. The test can differentiate between Plasmodium pan species, P. falciparum and P. vivax, and has a sensitivity of 84โ€“94%, a specificity of >92% and a limit of detection of 1โ€“2 parasites/ยต. Malaria-LAMP is the first molecular test for malaria that can identify P. vivax infections even in low-transmission settings, making an important contribution to global elimination efforts. Malaria-LAMP is a molecular test that works using loop-mediated isothermal amplification (LAMP).

To control malaria caused by P. vivax, sensitive and reliable tools are needed, especially in areas close to elimination. Different species require different treatment strategies, but while current diagnostic tests can identify P. falciparum, they are generally not able to differentiate between the various malaria species. There is currently no diagnostic that can effectively detect inactive parasites in the liver โ€“ which is why effective and highly sensitive blood-stage diagnosis is key.

"Loop-mediated isothermal amplification (LAMP) is a unique, temperature-independent technique for amplifying DNA that is simple to use, providing a visual display that is easy to read; additionally, the technique is robust and can be used at peripheral health centers." WHO Policy Guidance. The use of TB-LAMP for the diagnosis of pulmonary tuberculosis. August 2016.[1]